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Yet another "in mice" breakthrough. The cerebral cortex of a mouse has around 8–14 million neurons while in those humans there are more than 10–15 billion. So scale this outcome by literally 1000x more neurons and wake me when the chimps are remembering how to hold a long conversation.

> Yet another "in mice" breakthrough

I don’t get this take. Like yes, we aren’t mice, and everything that works in mice won’t work in humans. But loads of things that worked in mice did wind up working in humans, which is why most groundbreaking drugs over the past decades were first explored in mice, which is why we continue to use mouse models.


NAT is an eternal flame.

The hidden story is the depth of work required to replace a keyboard on a newer Lenovo. The amount of work is absurd. Easily an hour or two for the casual owner plus use of multiple tools. Don't blame the author for giving up on it.

https://www.ifixit.com/Guide/Lenovo+ThinkPad+X1+Carbon+6th+G...

"Step 26: Remove the seventy-two 0.5mm screws holding keyboard in place."


The 21st century version of this will be "Why did we use petrol for so long?"

I think it will be 'ads'.

Or pfas, plastic...

Obvious failure should be obvious. Get out of the streets. What happens when one gets a flat tire? Surely it doesn't just stop in the middle of the street, right??

We need anything that scales quickly, safely, and cheap. Just getting us through the duck curve would be a tremendous win for energy. https://en.wikipedia.org/wiki/Duck_curve


I've been running Win11 without a TPM for 6 years. Saying you can't upgrade isn't the same thing as Windows saying you can't upgrade. Knowing your OS seems to be a lost art. I'm not dismissing the valid complaint, but the title is empirically wrong clickbait.

The only Hard requirements are a CPU with SSE 4.2 and POPCNT. Win11 will simply not install on older CPUs. The rest of the requirements can be bypassed but Microsoft will block you from the annual major feature upgrades. You will have to do those manually too. They also claim that your stability and performance on pre-8th Gen CPUs will be degraded and they will give no support, but in reality it runs just fine. Win11 is sluggish on all CPUs anyway.

Win11 was released at the end of 2021. What were you running for 6?

Tried it when it was Win10 with a fancy name. Never had an issue with TPM or any other hardware requirements. https://betawiki.net/wiki/Windows_11_build_21242_(rs_prerele...

Because the Industrial Revolution is over and so is the first quarter of the 21st century! Peak oil already happened and they need to pivot to investing by 'buying everything'


There's a 4th way, but it works least often. Maybe Method 2.5 fits better: Wait for the problem to fix itself to your level of risk. Ex: This road is blocked. I have a good news it won't be blocked in X days/months/years. Let's just wait until it's a little better for us to travel down and do something else for a just little while. It's a hybrid between waiting for the path to open up for everyone and forcing your way through. Taking a stepping stone between changing the world and changing your solution to the problem.

My experience in trying to build AI tools has always been the 4th way :) Let’s build a coding agent in 2022, procrastination takes over, and then came along Aider, Cursor, Roo, and others. Same with AI observability tools. Wait just enough time to see the tools built themselves.

That 4th way is a nicely realistic but very toxic (in my experience) way to solve problems.

Not when it’s applicable in the situation but if you use it in your toolbox it’s very easy to overapply, if you’re a hammer everything looks like a nail style.

Use it critically


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