It is a interesting debate to have but this is unlikely to happen for consumer hardware, since no OEM wants you to have that kind of access(talking of those phone SoCs), they will just give you a slice of ccNUMA to protect their "IP". That qualcomm bug that he showed is unlikely to go away for consumers.

There is a message to build your own computers and that's probably what people will do and it could be interesting research for custom servers and future heterogeneous architectures. I suspect people in this industry are already doing it.