Blade Runner is pretty much THE gold standard when it comes to Cyberpunk cinema, and it's themes are pretty much everything you described. Blade Runner ain't no parody.
Good example. Yeah, it’s got most of that going on (plus some other things) and doesn’t obviously (though, a little, kinda, obliquely) feature either the plot or surface-level trappings of Frankenstein—so, it doesn’t look like parody.
My point was that if you want Cyberpunk’s “Frankenstein”, it’s probably not to be found in works that look too much like Frankenstein on the surface—those’ll just be borrowing tropes or tending toward parody, and won’t be Frankenstein-like in ways that matter.