I think the main issue for most casual users is the office suite and browser.
LibreOffice/OpenOffice.org unfortunately do not cut it for quirky functionality/aesthetics etc. The most polished alternatives Corel and WPS Office only WPSOffice have a ready deb/rpm installer while also having a collaboration feature inbuilt. Corel seems to have decided to concentrate on a windows only Law vertical , whererthey are admittedly not doing too bad.
Browsers should do most of whats neeed for the rest of the saas apps even the video collab apps like Teams/Zoom have a browser mode.
Latest Office or Microsoft365 is being turned almost into a Saas wrapper for the online app , while having an always on siphon for your data to the MScloud and ADs, so many intrusive ads all overthe place.
If its an older version that works i guess can be usable in a VM , but again this is for your casul office worker/parents etc.The least amount of friction will usually be best for adoption (see how zoom came out on top in the videochat space)